Elevating Radiopharmaceutical Research with Customized In Vivo Models
Radiopharmaceutical research is a complex and crucial field that requires specialized expertise and resources. Rdcthera specifically deals with providing full-service coverage for in vivo models development tailored for radiopharmaceutical studies. We pride ourselves on having a team of experts who can help you achieve your research goals with tailored solutions and exceptional support every step of the way.
In Vivo Models in Radiopharmaceutical Research
In vivo models are unique tools for studying radiopharmaceuticals. Such models allow the realization of the biological effects and radiopharmaceuticals distribution in a living organism, providing critical knowledge impossible to derive from in vitro studies. By modeling human diseases, researchers can use in vivo models in studying the pharmacokinetics, efficacy, and safety of radiopharmaceuticals and hence develop effective and safe therapeutic agents.
Fig.1. Radiopharmaceutical drug screen for in vivo cytotoxic effect size using zebrafish. (Kunos CA, et al., 2021)
Comprehensive In Vivo Model Development Services
Diverse Animal Models to Suit Your Research Needs
We employ small animals such as mice and rats for early stages of studies and larger models such as rabbits and non-human primates for more advanced evaluations.
We are proficient in developing a wide range of animal models to support your radiopharmaceutical research, including
- Spontaneous Models
- Experimentally Induced Models
- Transgenic Models
- Negative Models
-
Orphan Models
We can offer our services in the development of animal models in the following aspects of diseases
- Cancer
- Cardiovascular Disease
- Neurological Disease
-
Metabolic Disease
Customization Based on Specific Project Requirements
At Rdcthera, we develop the most appropriate animal model for your project by considering several key factors
- Model Availability
- Physiological Relevance
- Imaging Compatibility
- Research Objectives
- Measurement Needs
- Operational Requirements
- Study-Specific Factors
Administration and Sampling
Our team will ensure accurate radiopharmaceutical administration and systematized sampling procedures in a manner that helps us acquire data that could be as close to factual as possible. With these meticulous efforts, this will ensure the reliability of study outcomes and provide robust support for your research hypotheses.
- Intravenous
- Intramuscular
- Sublingual
- Intravitreal
- Subcutaneous
- Intraperitoneal
- Nasal
- Oral
- Transdermal
- Cassette Administration
- Intrathecal drug delivery
- Continuous Microblood Collection
Commitment to the 3Rs Principles
Rdcthera is deeply committed to working with the principles of 3Rs: Replacement, Reduction, and Refinement. We strive to replace animal models with alternative methods wherever possible, reduce the number of animals used, and refine our techniques to minimize animal suffering and improve welfare.
Applications of Our In Vivo Model Development Services
Our in vivo model development services cater to a very wide, diversified range of radiopharmaceutical research areas.
- Drug Discovery and Development
- Pharmacokinetics and Biodistribution
- Therapeutic Efficacy Studies
For more information on Rdcthera's in vivo models development services for radiopharmaceutical research, please contact us. We look forward to partnering with you to advance your research goals and drive innovation in the field of radiopharmaceuticals.
Reference
- Kunos CA, Howells R, Chauhan A, et al. (2021). Radiopharmaceutical Validation for Clinical Use. Front Oncol. 11:630827.
For research use only. Not intended for any clinical use.
Related Service
